US 6,649,777 B2Granted

C2 substituted taxanes

AssigneeFlorida State University

InventorsRobert A. Holton, Chunlin Tao

Life of this patent

Estimating the term…

Abstract

Taxane derivatives having alternative C2 substituents.

Claims13

Dependent claims

A taxane having the formula

wherein
Ac is acetyl,
Ph is phenyl, and
R is m-MeOPh, m-MePh, m-CIPh, m-CF3Ph, p-MeOPh, p-CIPh, p-FPh, o-CF3Ph, o-CH3Ph, m,m′-(CF3)2Ph, m,m′-(CH3)2Ph, or m-HOPh.

1 more element

Dependencies are inferred from the claim text.

Facts

Application: 10/021,738Filed 12 Dec 2001 · continuation
Priority: 29 Jan 1993
Published: US 2002/0058821 A116 May 2002
Granted: 18 Nov 2003
Term ends: Not estimatedThe source records don’t support an estimate.

Classification14 codes

C07D 407/12
Containing two hetero rings: linked by a chain containing hetero atoms as chain links
C07C 227/22
Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton: from lactams, cyclic ketones or cyclic oximes,…
C07C 231/12
Preparation of carboxylic acid amides: by reactions not involving the formation of carboxamide groups
C07C 233/87
With the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom: of a carbon skeleton…

Family

Application08/010,798Parent of this continuation-in-part · filed 29 Jan 1993
Application08/034,247Parent of this continuation-in-part · filed 22 Mar 1993
Application08/094,715Parent of this continuation · filed 20 Jul 1993
Application08/462,124Parent of this division · filed 5 Jun 1995
Application08/986,600Parent of this division · filed 8 Dec 1997
Application09/465,035Parent of this continuation · filed 16 Dec 1999
US 2002/0058821 A1Pre-grant publication · published 16 May 2002
US 6,339,164 B1Parent of this continuation
Application09/465,035Parent of this division
US 6,028,205 AParent of this division
Application08/986,600Parent of this continuation-in-part
US 5,399,726 AParent of this continuation-in-part
US 5,728,725 AParent of this division
Application08/462,124Parent of this continuation
Application08/094,715Parent of this continuation-in-part
US 5,430,160 AParent of this continuation-in-part
US 6,649,777 B2This patent

From the US filing history. Foreign family members aren’t listed.

Timeline

Citations

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Facts

Application

10/021,738Filed 12 Dec 2001 · continuation

Priority

29 Jan 1993

Published

US 2002/0058821 A116 May 2002

Granted

18 Nov 2003

Term ends

Not estimatedThe source records don’t support an estimate.

Classification14 codes

C07D 407/12
Containing two hetero rings: linked by a chain containing hetero atoms as chain links
C07C 227/22
Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton: from lactams, cyclic ketones or cyclic oximes,…
C07C 231/12
Preparation of carboxylic acid amides: by reactions not involving the formation of carboxamide groups
C07C 233/87
With the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom: of a carbon skeleton…

Family

Application08/010,798Parent of this continuation-in-part · filed 29 Jan 1993

Application08/034,247Parent of this continuation-in-part · filed 22 Mar 1993

Application08/094,715Parent of this continuation · filed 20 Jul 1993

Application08/462,124Parent of this division · filed 5 Jun 1995

Application08/986,600Parent of this division · filed 8 Dec 1997

Application09/465,035Parent of this continuation · filed 16 Dec 1999

US 2002/0058821 A1Pre-grant publication · published 16 May 2002

US 6,339,164 B1Parent of this continuation

Application09/465,035Parent of this division

US 6,028,205 AParent of this division

Application08/986,600Parent of this continuation-in-part

US 5,399,726 AParent of this continuation-in-part

US 5,728,725 AParent of this division

Application08/462,124Parent of this continuation

Application08/094,715Parent of this continuation-in-part

US 5,430,160 AParent of this continuation-in-part

US 6,649,777 B2This patent

From the US filing history. Foreign family members aren’t listed.