Stable salts of S-adenosyl-L-methionine (SAMe) and the process for their preparation
AssigneeOrchid Chemicals & Pharmaceuticals Limited
InventorsPandurang Balwant Deshpande, Udayampalam Palanisamy Senthilkumar, Subramaniam Ganesan
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Abstract
This invention relates to the production of new & stable salts of S-adenosyl-L-methionine SAMe). The source of SAMe used in the salt formation is from chemical process wherein stereoselective methylation of S-adenosyl-L-homocysteine is achieved. The process for the salt preparation is simple, efficient & reproducible on large scale. The new salts were found to be stable at accelerated temperature for minimum 3 months.
Claims3
A stable salt of S-adenosyl-L-methionine selected from the group consisting of S-adenosyl-L-methionine disulfate resorcinol-4,6-disulfonate, S-adenosyl-L-methionine disulfate catechol-3,5-disulfonate, S-adenosyl-L-methionine disulfate phenol-2,4,6-trisulfonate and a sodium salt thereof.
Dependencies are inferred from the claim text.