Biological production of stable glutamine, poly-glutamine derivatives in transgenic organisms and their use for therapeutic purposes
AssigneeUniversity of Virginia Patent Foundation
InventorsMichael P. Timko, Richard L. Guerrant
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Abstract
The invention provides a bioproduction of glutamine rich peptides. These peptides are used for rehydration and nutrition therapy in patients and for enhanced nutrition in animals. The peptides may be used as individual peptides or combined with other peptides in oligopeptides or proteins. Compositions of glutamine rich peptides and nucleic acid sequences for producing such peptides, as well as methods of production and use, are described.
Claims7
An isolated nucleic acid sequence comprising a coding region that encodes for a glutamine rich peptide, said peptide consisting of the sequence MET(ALA-GLN)n, -(protease cleavage site)-(ALA-GLN)n wherein n is a number ranging from 1 to 20.
Dependencies are inferred from the claim text.