Method of treating HIV infection by combined use of a cytotoxic agent and a non-nucleoside reverse transcriptase inhibitor
AssigneeBristol-Myers Squibb Company
InventorBruce D. Korant
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Abstract
This invention relates to a method of treating human immunodeficiency virus (HIV) infection in a mammal comprising administering to the mammal a therapeutically effective amount of a combination of: (i) at least one cytotoxic agent and (ii) at least one non-nucleoside reverse transcriptase HIV inhibitor (NNRTI). This invention also relates to a method of treating chronic viral infections comprising administering to the mammal a therapeutically effective amount of a combination of: (i) at least one cytotoxic agent and (ii) at least one antiviral agent.
Claims1
A method of treating human immunodeficiency virus (HIV) infection in a mammal consisting essentially of administering in combination to a mammal in need thereof, a therapeutically effective amount of:
- (i) a cytotoxic agent selected from the group consisting of losoxantrone and etoposide;
- and (ii) a non-nucleoside reverse transcriptase HIV inhibitor, wherein said non-nucleoside reverse transcriptase inhibitor is efavirenz.
Dependencies are inferred from the claim text.