Quinoline and quinazoline compounds useful in therapy

A compound of formula I,

• wherein
• R1 represents C1-4 alkoxy optionally substituted by one or more fluorine atoms;
• R2 represents an aryl group selected from phenyl or naphthyl or a heteroaryl group selected from pyridinyl or furanyl, each aryl or heteroaryl group optionally substituted by C1-4 alkyl or SO2NH2;
• R3 represents a heterocyclic ring selected from morpholine, thiomorpholine-1,1-dioxide, 1,4-dioxan, tetrahydrofuran, piperidine, optionally fused to a benzene or pyridine ring, or 1,4-benzodioxane, each ring system as a whole being optionally substituted by one or more groups independently selected from OH, C1-4 alkyl, C1-4 alkoxy, halogen and NHSO2(C1-4 alkyl);
• X represents N;
• and
• L is absent,
• or represents a cyclic group of formula Ia,
• in which A is attached to R3;
• A represents CO or SO2;
• Z represents CH or N;
• m represents 1 or 2, and in addition, when Z represents CH, it may represent 0;
• and
• n represents 1, 2 or 3, provided that the sum of m and n is 2,3,4 or 5;
• or represents a chain of formula Ib,
• in which A is attached to R-hu 2;
• A and Z are as defined above;
• R4 and R5 independently represent H or C1-4 alkyl;
• and
• p represents 1, 2 or 3, and in addition, when Z represents CH, it may represent 0;
• or a pharmaceutically acceptable salt thereof.