Substituted phenylcyclohexanecarboxamides and their use

A compound of the formula (I)

• in which
• D represents a radical
• in which
• R2 represents hydrogen, halogen, hydroxyl, carboxyl, cyano, nitro, trifluoromethyl, trifluoromethoxy, (C1-C6)-alkyl, C1-C6)-alkoxy or (C1-C6)-alkoxycarbonyl,
• A represents a group of the formula N—R5,
• in which
• R5 represents hydrogen, (C1-C6)-alkyl, (C3-C7)-cycloalkyl, where alkyl and cycloalkyl for their part may be substituted up to three times independently of one another by hydroxyl or mono- or di-(C1-C6)-alkylamino, represents (C6-C10)-aryl, 5- to 10-membered heteroaryl having up to three heteroatoms from the group consisting of N, O and S or 5- or 6-membered heterocyclyl having up to three heteroatoms from the group consisting of N, O and S, where aryl, heteroaryl and heterocyclyl for their part may be substituted up to three times independently of one another by halogen, hydroxyl, cyano, nitro, trifluoromethyl, trifluoromethoxy, (C1-C6)-alkyl, (C1-C6)-alkoxy, (C1-C6)-alkoxycarbonyl or mono- or alkylamino,
• R1 represents hydrogen, (C1-C6)-alkyl, which for its part may be substituted by hydroxyl or (C1-C4)-alkoxy, represents (C3-C7)-cycloalkyl, (C6-C10)-aryl, 5- to 10-membered heteroaryl having up to two heteroatoms from the group consisting of N, O and S, where aryl and heteroaryl for their part may be substituted independently of one another by halogen, or represents a radical of the formula —NR7R8 or —OR9,
• in which
• R7 and R8 independently of one another represent hydrogen, (C6-C10)-aryl, adamantyl, (C1-C8)-alkyl, whose chain may be interrupted by one or two oxygen atoms and which may be substituted up to three times independently of one another by hydroxyl, phenyl, trifluoromethyl, (C3-C8)-cycloalkyl, (C1-C6)-alkoxy, mono- or di-(C1-C6)-alkylamino, 5- or 6-membered heterocyclyl having up to three heteroatoms from the group consisting of N, O and S or by 5- to 10-membered heteroaryl having up to three heteroatoms from the group consisting of N, O and S, represent (C3-C8)-cycloalkyl, which may be substituted up to three times independently of one another by (C1-C4)-alkyl, hydroxyl or oxo, or represent 5- or 6-membered heterocyclyl having up to two heteroatoms from the group consisting of N, O and S, where N is substituted by hydrogen or alkyl, or
• R7 and R8 together with the nitrogen atom to which they are attached form a 4- to 7-membered saturated heterocycle which may contain up to two further heteroatoms from the group consisting of N, O and S and which is optionally substituted by hydroxyl, oxo or (C1-C6)-alkyl, which for its part may be substituted by hydroxyl, and
• R9 represents (C6-C10)-aryl, adamantyl, (C1-C8)-alkyl, whose chain may be interrupted by one or two oxygen atoms and which may be substituted up to three times independently of one another by hydroxyl, phenyl, trifluoroomethyl, (C3-C8)-cycloalkyl, (C1-C6)-alkoxy, mono- or alkylamino, 5- or 6-membered heterocyclyl having up to three heteroatoms from the group consisting of N, O and S or by 5- to 10-membered heteroaryl having up to three heteroatoms from the group consisting of N, O and S, represents (C3-C8)-cycloalkyl, which may be substituted up to three times independently of one another by (C1-C4-alkyl, hydroxyl or oxo, or represents 5- or 6-membered heterocyclyl having up to two heteroatoms from the group consisting of N, O and S, where N is substituted by hydrogen or (C1-C4)-alkyl,
• R3 represents (C1-C8)-alkyl, whose chain may be interrupted by a sulphur or oxygen atom or an S(O) or SO2 group, represents phenyl, benzyl or 5- or 6-membered heteroaryl having up to two heteroatoms from the group consisting of N, O and S, where phenyl, benzyl and heteroaryl may be substituted up to three times independently of one another by halogen, trifluoroomethyl, cyano, nitro, hydroxyl, (C1-C6)-alkyl or (C1-C6)-alkoxy, and
• R4 represents a radical of the formula —C(O)—NR10R11,
• in which
• R10 and R11 independently of one another represent hydrogen or (C1-C6)-alkyl,
• with the proviso that at least one heteroaryl moiety or heterocyclyl moiety as defined hereinabove is present in said compound,
• or a pharmaceutically acceptable salts, hydrates, hydrates of the salts or solvates thereof.