Method for using and making a fiber array
AssigneeApplera Corporation
InventorsCharles S. Vann, Tim Geiser, Andrew J. Blasband
Life of this patent
Estimating the term…
Abstract
The invention provides a method for contacting at least two chemical species by immobilizing an immobilized chemical species on a fiber, placing the fiber on a support having a channel, and disposing a mobile chemical species into the channel such that the immobilized chemical species contacts the fiber. The invention also provides methods for analyzing the contact between at least two chemical species, detecting the binding of two chemical species, making a microchip, and synthesizing a chemical species on a fiber.
Claims21
A method for analyzing the contact between two chemical species comprising:
- contacting only a first surface portion of an optical fiber with a first mobile chemical species;
- contacting only a second surface portion of said optical fiber different to said first surface portion, with a second mobile chemical species different from said first mobile chemical species, wherein said optical fiber has an immobilized chemical species immobilized on said first surface portion and said second surface portion;
- detecting whether binding occurs between said immobilized chemical species and said first mobile chemical species;
- detecting whether binding occurs between said immobilized chemical species and said second mobile chemical species.
A method for analyzing the contact between two chemical species comprising:
- contacting only a first surface portion of an optical fiber with a first mobile chemical species;
- contacting only a second surface portion of said optical fiber different to said first surface portion, with a second mobile chemical species different from said first mobile chemical species, wherein said optical fiber has an immobilized chemical species immobilized on said first surface portion and said second surface portion;
- and
- directing a light at an end of said optical fiber;
- detecting excitation light emitted from binding between said immobilized chemical species and said first mobile chemical species;
- and
- detecting excitation light emitted from binding between said immobilized chemical species and said second mobile chemical species.
Dependencies are inferred from the claim text.