Recombinant Chlamydia trachomatis PGP3 antigen
AssigneeChiron Corporation
InventorGiulio Ratti
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Abstract
A new recombinant form of the plasmid-encoded protein pgp3 from C. trachomatis, serotype D, to be used in immunogenic compositions and in the preparation of immunogenic compositions was purified by ion exchange column chromatography and shown to be suitable for quantitative immunoassy on clinical samples in an ELISA format.
Claims2
An immunogenic composition comprising a recombinant Chlamydia trachomatis pgp3 protein having its native amino acid conformation and a pharmaceutically acceptable carrier, wherein the recombinant Chlamydia trachomatis pgp3 protein is unmodified by recombinant expression, and wherein the recombinant Chlamydia trachomatis pgp3 protein can detect antibodies against conformational epitopes.
Dependencies are inferred from the claim text.