Sertoli cells as transplantation facilitator for cell transplantation
AssigneeUniversity of South Florida
InventorsPaul R. Sanberg, Don F. Cameron, Cesario V. Borlongan
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Abstract
A method of producing a sustained localized immunosuppressive effect in localized tissues is achieved by transplanting Sertoli cells proximate to the tissue.
Claims5
A method of producing a sustained localized immunosuppressive effect in target tissue with a mammal, said method comprising co-transplanting Sertoli cells and neural cells to the target tissue, wherein the neural cells are first co-cultured with the Sertoli cells and wherein the co-cultured trasplant cells and Sertoli cells are co-transplanted together to the target tissue.
A method of producing a sustained localized immunosuppressive effect in neural tissue within a mammal, said method comprising co-transplanting Sertoli cells and neural cells to the neural tissue, wherein the neural cells are first co-cultured with the Sertoli cells and the co-cultured neural cells and Sertoli cells are co-transplanted together to the neural tissue.
A method of producing a sustained localized immunosuppressive effect in neural tissue within a mammal suffering from a neurological disorder, said method comprising co-transplanting Sertoli cells and neural cells to the neural tissue, wherein the neural cells are first co-cultured with the Sertoli cells and the co-cultured neural cells and Sertoli cells are co-transplanted together to the neural tissue.
Dependencies are inferred from the claim text.