Aluminum-zirconium antiperspirant salts with high peak 5 Al content
AssigneeThe Gillette Company
InventorsAngel L. Carrillo, Richard Oryszczak, Yan-Fei Shen
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AssigneeThe Gillette Company
InventorsAngel L. Carrillo, Richard Oryszczak, Yan-Fei Shen
Estimating the term…
Disclosed are enhanced efficacy aluminum-zirconium antiperspirant salt compositions which exhibit an HPLC peak 5 area content of about 33% or more, preferably at least 45%, more preferably at least 50%, most preferably at least 55%. Especially preferred are aluminum-zirconium antiperspirant salt compositions which, in addition to the aforementioned high peak 5 content, also exhibit an HPLC peak 4 to peak 3 area ratio of at least 0.4, preferably at least 0.7. The aforementioned salt compositions will preferably have a metal (Al+Zr) to chloride (or anion) ratio of about 0.90 to about 1.00. Also disclosed are methods of making such antiperspirant salt compositions and aqueous solutions of such antiperspirant salt compositions. Further disclosed are topical compositions comprising a dermatologically acceptable carrier vehicle and a perspiration reducing effective amount of an aluminum-zirconium antiperspirant salt composition as described above.
An aluminum-zirconium octachlorohydrate having a metal (Al+Zr) to chloride molar ratio of 0.90 to 1.00.
An aluminum-zirconium octachlorohydrate having the formula AlnZr(OH)[3n+4−m(n+1)](Cl)[m(n+1)]-(Gly)q wherein n is 6.0 to 10.0, m is 1.00 to 1.11, and q is about 0.8 to about 4.0.
A method of preparing an aluminum-zirconium chlorohydrate of the formula AlnZr(OH)[3n+4−m(n+1)](Cl)[m(n+1)]-(Gly)q wherein n is 2.0 to 10.0, m is 1.00 to 1.11, and q is about 0.8 to about 4.0, which method comprises mixing an aqueous solution of an aluminum chlorohydrate of the formula A12(OH)6-aCla wherein a is about 1 to about 2, with an aqueous solution comprising glycine and a zirconium hydroxychloride of the formula Zr(OH)4-bClb wherein b is 2.2 to 4.0, each of said aluminum chlorohydrate and zirconium hydroxychloride being present in an amount to provide an Al:Zr molar ratio of 2.0 to 10.0, and, if necessary, adjusting the metal (Al+Zr) to chloride ratio (M:Cl) to 0.90 to 1.00 by addition of an appropriate amount of aqueous HCL.
Dependencies are inferred from the claim text.