Labeled compounds for measuring the function of the muscarinic acetylcholine nervous system
AssigneeHamamatsu Photonics K.K.
InventorsHideo Tsukada, Kengo Sato, Shingo Nishiyama, Norihiro Harada
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Abstract
A muscarinic acetylcholine nervous system labeled compound for positron emission tomography measurement of the present invention has a structure represented by undermentioned general formula (I): [in the formula, W represents one selected from the group consisting of groups represented by undermentioned formulae (II) and (III): (in the formulae, R represents one selected from the group consisting of an 11C-labeled ethyl group and an 11C-labeled propyl group), and in the case that W is a group represented by above-mentioned formula (II), above-mentioned formula (I) is the (+)-isomer].
Claims3
A compound for labeling muscarinic acetyicholine receptors in the central nervous system for positron emission tomography measurement, wherein the compound is represented by the following general formula (I):
- where W is one of the groups represented by the following formulae (II) and (III):
- where R is a 11C-labeled ethyl group or a 11C-labeled propyl group, such that when W is a group represented by formula (II), then formula (I) is the (+)-isomer.
Dependencies are inferred from the claim text.