Supported osmates, process for preparation thereof, and a process for the preparation of chiral vicinal diols using supported osmate catalyst
AssigneeCouncil of Scientific and Industrial Research
InventorsBoyapati Manoranjan Choudary, Naidu Sreenivasa Chowdari, Mannepalli Lakshmi Kantam, Kondapuram Vijaya Raghavan
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Abstract
The present invention provides a supported osmate useful as a reusable catalyst in the preparation of vicinal diols. The present invention also relates to a process for the preparation of supported osmates of the formula (S—NR3)2OsO4.nH2O wherein S is a support, R is an alkyl group, n is the number of water molecules and use thereof in the preparation of vicinal diols by asymmetric dihydroxylation (AD) of olefins in presence of cinchona alkaloid compounds.
Claims11
A process for the preparation of vicinal diols comprising asymmetrically dihydroxylating the corresponding olefin in the presence of a cinchona alkaloid using an oxidant in a solvent selected from the group consisting of water, acetone, acetonitrile, t-butanol and any mixture thereof, at a temperature in the range of −70 to 100° C. for a period in the range of 0.5 to 24 hours, and in the presence of a catalytic amount of a heterogeneous supported osmate catalyst of the general formula S—NR3)2OsO4.nH2O wherein S is a support, R is an alkyl group, n is the number of water molecules, and recovering the pure vicinal diol.
Dependencies are inferred from the claim text.