Loading patent…
AssigneeEgis Gyogyszergyar Rt.
InventorsZoltan Greff, Peter Kotay Nagy, Jozsef Barkoczy, Gyula Simig, Laszlo Balazs, Imre Doman, Zoltan Ratkai, Peter Seres, Zsuzsa Szent Kirallyi, Ferenc Barta, Gyorgyi Vereczkeyne Donath, Kalman Nagy
Estimating the term…
The invention relates to a process for the preparation of amorphous atorvastatin calcium by recrystallization of crude atorvastatin from an organic solvent which comprises dissolving crude amorphous atorvastatin calcium in a lower alkanol containing 2-4 carbon atoms or a mixture of such alkanols under heating and isolating the amorphous atorvastatin calcium precipitated after cooling. The atorvastatin calcium obtained is a known valuable agent useful in treating hyperlipidemia and hypercholestrolemia.
Process for the preparation of amorphous atorvastatin calcium by dissolving crude atorvastatin calcium in an organic solvent, which comprises dissolving crude atorvastatin calcium in a lower alkano containing 2-4 carbon atoms or in a mixture of such alkanols under heating and isolating the amorphous atorvastatin calcium precipitated after cooling.
Dependencies are inferred from the claim text.