US 6,645,966 B2Granted

Treatment of malaria with farnesyl protein transferase inhibitors

AssigneeSchering Corporation

InventorsWilliam T. Windsor, Patricia C. Weber, Corey O. Strickland, Michael Gelb

Life of this patent

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Abstract

Disclosed is a method of treating Malaria comprising administering an effective amount of an FPT inhibitor to a patient in need of such treatment alone or in combination with an additional antimalarial agent and/or agent for reversing antimalarial resistance. Also disclosed are novel Farnesyl Protein Transferase inhibitors.

Claims9

Dependent claims

A method for treating malaria comprising administering to a human in need of such treatment an effective amount of a compound selected from:

Dependencies are inferred from the claim text.

Facts

Application: 10/053,335Filed 18 Jan 2002 · us provisional application
Priority: 22 Jan 2001
Published: US 2003/0092705 A115 May 2003
Granted: 11 Nov 2003
Term ends: Not estimatedThe source records don’t support an estimate.

Classification17 codes

C07D 231/12
Having two or three double bonds between ring members or between ring members and non-ring members: with only hydrogen atoms, hydrocarbon or…
A61K 31/4178
1,3-Diazoles: not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
A61K 31/454
Containing further heterocyclic ring systems: containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
A61K 31/4545
Containing further heterocyclic ring systems: containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine

Family

Application60/263,277Us provisional application · filed 22 Jan 2001
US 2003/0092705 A1Pre-grant publication · published 15 May 2003
US 6,645,966 B2This patent

From the US filing history. Foreign family members aren’t listed.

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