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US 6,645,946 B1Granted
Delivery of a therapeutic agent in a formulation for reduced toxicity
AssigneePro-Pharmaceuticals, Inc.
InventorsAnatole Klyosov, David Platt
Life of this patent
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Abstract
Methods and compositions for reducing toxicity of a toxic agent are provided in which a polysaccharide, galactomannan is coadministered with a therapeutic agent in a liquid formulation to a subject to reduce toxicity of the agent for the subject.
Claims16
A method of reducing the toxic side effects of a chemotherapeutic agent in a subject, comprising:
- providing a galactomannan polysaccharide;
- combining an effective amount of the polysaccharide with the effective dose of the agent in a mixture, wherein said effective amount of said polysaccharide is an amount sufficient to reduce toxic side effects of said agent;
- formulating the mixture for parenteral administration to the subject;
- and
- administering the mixture to the subject.
2 more elements
A method of reducing the toxic side effects of a chemotherapeutic agent in a subject, comprising:
- providing an effective amount of galactomannan polysaccharide, wherein said effective amount of said polysaccharide is an amount sufficient to reduce toxic side effects of said agent;
- providing the effective dose of the agent;
- and
- parenterally administering the effective amount of the polysaccharide and the effective dose of the agent to the subject either sequentially or together.
1 more element
Dependencies are inferred from the claim text.