Method of treating diseased, injured or abnormal cartilage with hyaluronic acid and growth factors
AssigneeDepuy Acromed, Inc.
InventorsMichael Radomsky, Mohammad A. Heidaran
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Abstract
A composition is provided for treating diseased, injured or diseased cartilage comprising hyaluronic acid and a growth factor. The composition has a viscosity and biodegradability sufficient to persist at the site for a period of time sufficient to alleviate the symptoms of the disease, injury or abnormality. Preferably hyaluronic acid is used in a composition range of 0.01-4% by weight and the preferred growth factor is IGF-I, present in a concentration range of about 10−6 to 100 mg/ml.
Claims14
A method of treating diseased, injured or abnormal cartilage comprising the step of applying to a site of diseased, injured or abnormal cartilage a liquid composition comprising an effective amount of a mixture of hyaluronic acid and a growth factor sufficient to alleviate the symptoms of the disease, injury or abnormality, wherein said composition has a viscosity and biodegradability sufficient to persist at said site for a period of time sufficient to alleviate said symptoms.
Dependencies are inferred from the claim text.