Polynucleotide compositions encoding broad-spectrum δ endotoxins
AssigneeMonsanto Technology LLC
InventorsThomas Malvar, Amy Jelen Gilmer
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Abstract
Disclosed, are novel synthetically-modified B. thuringiensis chimeric crystal proteins having improved insecticidal activity against coleopteran, dipteran and lepidopteran insects. Also disclosed are the nucleic acid segments encoding these novel peptides. Methods of making and using these genes and proteins are disclosed as well as methods for the recombinant expression, and transformation of suitable host cells. Transformed host cells and transgenic plants expressing the modified endotoxin are also aspects of the invention.
Claims8
An insecticidal hybrid delta-endotoxin protein, with an insecticidal segment comprising domains I and II of a first native B. thuringiensis delta-endotoxin Cry1A protein, domain III of a second native B. thuringiensis delta-endotoxin Cry1F protein, and all or a portion of a protoxin segment of a native delta endotoxin Cry1A, Cry1F or combination Cry1F-Cry1A protein.
Dependencies are inferred from the claim text.