Polar silanes and their use on silica supports
AssigneeDionex Corporation
InventorsXiaodong Liu, Andrei V. Bordunov
Life of this patent
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Abstract
A modified silica support having a polar phase bound to its surface and suitable for use for chromatographic separations, having the following formula: wherein, m=0-20; n=0-20; p=1-50; X is sulfonyl, carbonyl, carbamoyl, or oxycarbonyl; R1=H, alkyl, substituted alkyl, aryl or substituted aryl groups; R2=alkyl, substituted alkyl, aryl or substituted aryl groups; and R3 and R4 are alkyl, aryl, hydroxyl, or alkoxyl groups or groups including oxygen atoms cross-linked to silicon atoms. Also, a polar silane intermediate to make this support.
Claims6
A modified silica Support having a a polar phase bound to its surface and suitable for use for chromatographic separations, said modified silica support having the following formula:
- wherein,
- m=0-20;
- n=0-20;
- p=1-50;
- X is sulfonyl, carbonyl, carbamoyl or oxycarbonyl;
- R1=H, alkyl, substituted alkyl, aryl or substituted aryl groups;
- R2=alkyl, substituted alkyl, aryl, or substituted aryl groups;
- and
- R3 and R4 are alkyl, aryl, hydroxyl, or alkoxyl groups, or groups including oxygen atoms cross-linked to silicon atoms.
Dependencies are inferred from the claim text.