Drug delivery systems and methods

A drug injection device comprising:

• a housing having a port that receives a standard container of fluid, said port comprising a longitudinal axis;
• a pressurizing mechanism that pressurizes the container to move the fluid;
• a penetrating member movable, along a displacement axis, from a storage position in the housing to an injection position extending outside the housing, said penetrating member being in fluid communication with the container;
• a penetrating member retraction mechanism for retracting said penetrating member into said housing after delivering one dose of the fluid;
• a sealing member to maintain the injectable fluid in an upper end of the housing;
• wherein said longitudinal axis and said displacement axis are not parallel nor coaxial;
• and
• wherein the penetrating member includes a first end to pierce skin of the body being injected and a second end to pierce the sealing member after the first end has penetrated the skin.

A method of drug delivery comprising the steps of:

• providing a housing having a first port that receives a first standard container of fluid along a first axis;
• pressurizing the fluid in the first standard container;
• moving an injection penetrating member from a storage position to an injection position along a second axis, the injection penetrating member being in fluid communication with the first standard container;
• retracting said penetrating member into said housing after delivering one dose of the fluid;
• providing a movable member slidable and sealingly positioned within the first port, the movable member fixedly supporting a first penetrating member in fluid communication with the container;
• collapsing a collapsible volume with the movable member upon insertion of the first container into the first port, the collapsible volume being in sealed communication with the first penetrating member to pressurize the container;
• and
• wherein said first axis and said second axis are not parallel nor coaxial.

A method of drug delivery comprising the steps of:

• providing a housing having a first port that receives a first standard container of fluid along a first axis and having a second port in the housing that receives a second standard container that pressurizes the fluid in the first standard container as said second standard container contains a fluid to be transferred into the first standard container,
• pressurizing the first standard container upon the transfer of the fluid;
• moving an injection penetrating member from a storage position to an injection position along a second axis, the injection penetrating member being in fluid communication with the first standard container;
• retracting said penetrating member into said housing after delivering one dose of the fluid;
• and
• wherein said first axis and said second axis are not parallel nor coaxial.

A method of drug delivery comprising the steps of:

• providing a housing having a first port that receives a first standard container of fluid along a first axis;
• pressurizing the fluid in the first standard container;
• moving an injection penetrating member from a storage position to an injection position along a second axis;
• penetrating the body with a first end of the injection penetrating member and then coming into fluid communication with the injectable fluid with a side opening of the injection penetrating member;
• retracting said injection penetrating member into said housing after delivering one dose of the fluid;
• and
• wherein said first axis and said second axis are not parallel nor coaxial.

A method of drug delivery comprising the steps of:

• providing a housing having a first port that receives a first standard container of fluid along a first axis;
• pressurizing the fluid in the first standard container;
• moving an injection penetrating member from a storage position to an injection position along a second axis, the injection penetrating member being in fluid communication with the first standard container;
• retracting said penetrating member into said housing after delivering one dose of the fluid;
• and
• locking the injection penetrating member within the housing after injection;
• and
• wherein said first axis and said second axis are not parallel nor coaxial.