Apparatus and method of laser dissociation for mass spectrometry
AssigneeAgilent Technologies, Inc.
InventorsStuart C Hansen, Christian A. Le Cocq, Gangqiang Li, Scott W Corzine
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Abstract
Mass spectometer system and method of use are disclosed. Briefly described, one embodiment of the mass spectrometry system, among others, includes a radio frequency multipole assembly, an inner structure, and a laser diode array system. The inner structure has an outside, an inside, and an opening. The inner structure substantially surrounds the radio frequency multipole assembly. The laser diode array system is disposed on the outside of the inner structure adjacent the side opening such that laser radiation emitted from the laser diode array system travels through the side opening.
Claims25
A mass spectrometry system, comprising:
- a radio frequency multipole assembly;
- an inner structure having an outer surface, an inner surface, and an opening, wherein the inner structure substantially surrounds the radio frequency multipole assembly;
- and
- a laser diode array system disposed on the outer surface of the inner structure adjacent the opening such that laser radiation emitted from the laser diode array system travels through the opening.
A mass spectrometry system, comprising:
- a radio frequency multipole assembly;
- an inner structure having a first side opening, wherein the inner structure substantially surrounds the radio frequency multipole assembly;
- a outer structure having a second side opening, wherein the outer structure substantially surrounds the inner structure, and wherein the first side opening and a second side opening are substantially aligned;
- and
- a laser diode array system, wherein the laser diode array system is disposed on an outer surface of the outer structure adjacent the second side opening such that laser radiation emitted from the laser diode array system is directed through the second side opening and the first side opening.
A mass spectrometry system, comprising:
- an ion source;
- a dissociation celulaser diode array system;
- wherein the dissociation cell/laser diode array system includes:
- a radio frequency multipole assembly,
- a structure that substantially surrounds the radio frequency multipole assembly, and
- a laser diode array system disposed on the outer surface of the structure;
- and
- a mass analyzer.
A method of dissociating an ion, comprising:
- producing the ion;
- focusing the ion into a dissociation celulaser diode array system, wherein the dissociation celulaser diode array system includes a radio frequency multipole assembly, a structure that substantially surrounds the radio frequency multipole assembly, and a laser diode array system disposed on the outer surface of the structure;
- producing laser radiation with a laser diode array system;
- and
- photodissociating the ion.
Dependencies are inferred from the claim text.