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US 6,642,435 B1Granted
Plant folate biosynthetic genes
AssigneeE. I. Du Pont de Nemours and Company
InventorsJ. Antoni Rafalski, Zude Weng, Leslie T. Harvell
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Abstract
This invention relates to an isolated nucleic acid fragment encoding a folate biosynthetic enzyme. The invention also relates to the construction of a chimeric gene encoding all or a portion of the folate biosynthetic enzyme, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the folate biosynthetic enzyme in a transformed host cell.
Claims12
An isolated polynucleotide comprising:
- (a) a nucleotide sequence encoding a polypeptide having tetrahydrofolylpolyglutamate synthase/folylpolyglutamate synthase activity, wherein the amino acid sequence of the polypeptide and the amino acid sequence of SEQ ID NO:14 have at least 80% sequence identity based on the Clustal alignment method, or
- (b) the complement of the nucleotide sequence.
Dependencies are inferred from the claim text.