US 6,642,370 B1 · Genetic marker for autoimmune disorder

Abstract

A mutation in an allele of the gene encoding the CD2BP1 protein is identified as a causative factor in familial recurrent arthritis. Methods of diagnosis and methods of screening for effectors of the mutated protein binding and function are disclosed.

Claims9

Dependent claims

An isolated nucleic acid molecule or the complement thereof, wherein said molecule encodes an amino acid sequence comprising the sequence of SEQ ID NO:19.

Dependencies are inferred from the claim text.

Facts

Application

09/710,693Filed 8 Nov 2000

Granted

4 Nov 2003

Term ends

Not estimatedThe source records don’t support an estimate.

Classification6 codes

G01N 33/564
Immunoassay; Biospecific binding assay; Materials therefor: for pre-existing immune complex or autoimmune disease , i.e. systemic lupus…
C12Q 1/6883
Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes: for diseases caused by alterations of genetic material
C12Q 2600/156
Oligonucleotides characterized by their use: polymorphic or mutational markers
G01N 2800/24
Detection or diagnosis of diseases: immunology or allergic disorders

Genetic marker for autoimmune disorder

Life of this patent

Abstract

Claims9

Genetic marker for autoimmune disorder

Life of this patent

Abstract

Claims9