Formulation for respiratory tract administration
AssigneeEuro-Celtique S.A.
InventorsMark Alfonso, Paul Goldenheim, Richard Sackler
Life of this patent
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Abstract
A dosage form for intranasal and/or inhalation administration of an analgesic having low opioid receptor binding activity to a warm blooded animal, that includes a pharmaceutically effective amount of the analgesic. A preferred analgesic is tramadol, a tramadol and/or a pharmaceutically acceptable salt, metabolite or derivative thereof. Methods of making and using the formulation according to the invention are also provided.
Claims12
An intranasal tramadol formulation comprising an active agent consisting essentially of tramadol in a form selected from the group consisting of tramadol free base, pharmaceutically acceptable salts thereof and any combinations thereof;
- said tramadol being dispersed within a pharmaceutically acceptable carrier for intranasal administration;
- said formulation being contained in a pharmaceutically acceptable dispenser for intranasal administration which dispenses an amount of said formulation to the mucousal surfaces in the nasal passages of a mammal to provide intranasal absorption of an analgesically effective amount of said tramadol.
Dependencies are inferred from the claim text.