Detoxication of active pharmaceutical substances using cyclodextrine oligomers

A cyclodextrin oligomer having the general formula

• CD—X—A—X—B—X—A—X—CD
• wherein X—A—B—X—A—X is a bifunctional spacer in which:
• each X is selected from the group consisting of —NH—, —O—, —S—, —C(═O)— and a covalent bond;
• each A is selected from the group consisting of a C2 to C4 alkylidenyl residues and a covalent bond;
• B is selected from the group consisting of diradical linkers derived from melamine, 1,3,5-benzenetricarboxylic acid (aka trimesic acid), a tetracarboxylic acid derivative of 1,2-dihydroxyanthraquinone, a tetraamino derivative of 1,2-anthraquinone, α-cyclodextrin, β-cyclodextrin and γ-cyclodextrin;
• wherein each said cyclodextrin is bound through two primary carbons;
• and
• each terminal CD is bound through a secondary carbon;
• and
• wherein said cyclodextrin oligomer is optionally substituted with at least one affinity group which interacts with a molecular target structure.