Methods of using pomegranate extracts for causing regression in lesions due to arteriosclerosis in humans
AssigneeStewart and Lynda Resnick Revocable Trust
InventorsMichael Aviram, Leslie Dornfeld
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Abstract
Methods of using pomegranate extracts of the present invention for treating patients with atherosclerosis, or increased intima-media thickness of an artery, are provided. The methods comprise the step of administering to the patient a composition comprising a therapeutically effective amount of an extract from pomegranate. The methods of the present invention may also be used to decrease the incidence of stroke or heart attack in a patient.
Claims24
A method of treating a patient with arteriosclerosis, comprising the step of administering to the patient a composition comprising a therapeutically effective amount of an extract from pomegranate, wherein the extract is prepared by a process comprising the steps of:
- (a) crushing and squeezing the whole fruits of pomegranate including inner and outer peels and the seeds to yield a juice component and an insoluble by-product component;
- and
- (b) separating the soluble juice component from the insoluble by-product component and removing the insoluble by-product component therefrom to produce the extract.
A method of treating a patient with an increased intima-media thickness of an artery, comprising the step of administering to the patient a composition comprising an amount of an extract from pomegranate which is therapeutically effective to reduce the intima-media thickness of the artery, wherein the extract is prepared by a process comprising the steps of:
- (a) crushing and squeezing the whole fruits of pomegranate including inner and outer peels and the seeds to yield a juice component and an insoluble by-product component;
- and
- (b) separating the soluble juice component from the insoluble by-product component and removing the insoluble by-product component therefrom to produce the extract.
A method of decreasing the incidence of stroke or heart attack in a patient, comprising the step of administering to the patient a composition comprising a therapeutically effective amount of an extract from pomegranate, wherein the extract is prepared by a process comprising the steps of:
- (a) crushing and squeezing the whole fruits of pomegranate including inner and outer peels and the seeds to yield a juice component and an insoluble by-product component;
- and
- (b) separating the soluble juice component from the insoluble by-product component and removing the insoluble by-product component therefrom to produce the extract.
The method of claim 23, wherein step (a) further comprises enzymatically treating the whole fruits of pomegranate including inner and outer peels and the seeds.
Dependencies are inferred from the claim text.