Cellular proteins which mediate herpesvirus entry
AssigneeNorthwestern University
InventorsPatricia G. Spear, Morgyn S. Warner, Robert J. Geraghty, Wanda M. Martinez, Rebecca I. Montgomery, Gary H. Cohen, Roselyn J. Eisenberg, Charles J. Whitbeck, Claude Krummenacher
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Abstract
A cellular herpesvirus entry protein, or a mutant, a homolog, a derivative, a variant or a biologically active fragment thereof, suspended in a pharmaceutically active carrier in an amount effective to inhibit entry of an alphaherpesvirus into a cell, wherein the cellular herpesvirus entry protein is a member of the immunoglobulin superfamily, is provided and method of use thereof
Claims3
A cellular herpesvirus entry protein consisting of the polypeptide set forth in SEQ ID NO:4 suspended in a pharmaceutically active carrier.
An isolated nucleic acid consisting of SEQ ID NO:4.
Dependencies are inferred from the claim text.