Pressurized aerosol compositions comprising powdered medicament dispersed in hydrofluoroalkane
AssigneeFisons Limited
InventorsSuresh N Mistry, Mark Gibson
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Abstract
Pressurized aerosol composition for administration by inhalation comprising a liquefied hydrofluoroalkane, a powdered medicament dispersed therein, and a suspending agent comprising a polymer soluble in the liquefied hydrofluoroalkane which is selected from polymers including recurring amide containing structural units, copolymers of amide containing units and carboxylic acid ester units, polyvinylacetate and acrylic acid/methacrylic acid ester copolymers.
Claims32
A pressurized suspension aerosol composition comprising a liquefied hydrofluoroalkane, a powdered medicament dispersed therein, wherein the medicament particles in said powdered medicament have a mass median diameter of 0.01 to 10 microns, and a suspending agent comprising a polymer soluble in the liquefied hydrofluoroalkane, said polymer being present in an amount of 0.00001 to 10% w/w, said polymer being different from said powdered medicament and being selected from the group consisting of polymers including recurring 1-ethylene-pyrrolidin-2-one units, copolymers of 1-ethylene-pyrrolidin-2-one units and vinylacetate units, polyvinylacetate and acrylic acid/methacrylic acid ester copolymers, and wherein said aerosol composition is for administration by inhalation.
Dependencies are inferred from the claim text.