Lactam-aldehyde compound and process of preparing same
AssigneeNational Institute of Advanced Industrial Science and Technology
InventorsHiroshi Izumi, Shigeru Futamura
Life of this patent
Estimating the term…
Abstract
A lactam-aldehyde compound represented by the formula (I) shown in the specification. The lactam-aldehyde compound may be prepared by subjecting a lactone-imine compound represented by formula (III) shown in the specification to an isomerization reaction. The precursor lactone-imine compound may be prepared by rearrangement of a 3,5-dioxa-12-azawurtzitane compound.
Claims7
A lactam-aldehyde compound represented by the following formula (I):
- wherein R1 represents an alkyl group, R2 represents an organic group.
A lactone-imine compound represented by the following formula (III):
- wherein R1 is as defined above, R3 is an amino acid side chain group and R4 is a hydroxyl group or a peptide chain.
A process for the production of a lactam-aldehyde compound of the following formula (II):
- wherein R1 represents an alkyl group, R3 is an amino acid side chain group and R4 is a hydroxyl group or a peptide chain, said process comprising subjecting a lactone-imine compound to an isomerization reaction, said lactone-imine compound being represented by the following formula (III):
- wherein R1, R3 and R4 are as defined above.
A process for the production of a lactone-imine compound of the following formula (III):
- wherein R1 represents an alkyl group, R3 is an amino acid side chain group and R4 is a hydroxyl group or a peptide chain, said process comprising subjecting a 3,5-dioxa-12-azawurtzitane compound to molecular rearrangement, said 3,5-dioxa-12-azawurtzitane compound being represented by the following formula (IV):
- wherein R1 represents an alkyl group, R3 is an amino acid side chain group and R4 is a hydroxyl group or a peptide chain.
Dependencies are inferred from the claim text.