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US 6,639,056 B2Granted
Antibodies specifically reactive with integrin β6 subunits
AssigneeThe Regents of the University of California
InventorsDean Sheppard, Robert Pytela
Life of this patent
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Abstract
The present invention provides anti-β6-antibodies that block attachment of αvβ6 to its ligands such as fibronection and tenascin.
Claims3
An antibody that specifically reacts with a β6 integrin subunit as displayed in SEQ ID NO:
- 27, wherein the antibody blocks the attachment of an αvβ6 integrin comprising the β6 integrin subunit to a ligand selected from the group consisting of fibronectin and tenascin when the antibody is contacted to the αvβ6 integrin.
Dependencies are inferred from the claim text.