HCV-derived RNA polymerase gene
AssigneesTetsuya Toyoda, International Reagents Corporation, Chugai Seiyaku Kabushiki Kaisha
InventorsTetsuya Toyoda, Michinori Kohara, Kyoko Kohara, Kazuhiro Higashi, Masayuki Tsuchiya
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Abstract
The present invention provides a gene encoding an RNA polymerase which plays an important role in the reproduction of hepatitis C virus, and a method of screening using this gene or this RNA polymerase protein, thereby allowing easy performance of screening for substances which inhibit the RNA polymerase playing an important role in HCV reproduction.
Claims6
An isolated nucleic acid encoding a protein comprising the amino acid sequence represented in SEQ ID NO:2.
An isolated nucleic acid encoding a protein comprising the amino acid sequence in which one amino acid is deleted from or added to the amino acid sequence represented in SEQ ID NO:2, and having RNA polymerase activity.
An isolated protein comprising the amino acid sequence represented in SEQ ID NO:2 and having RNA polymerase activity.
An isolated protein comprising the amino acid sequence in which one amino acid is deleted from or added to the amino acid sequence represented in SEQ ID NO:2, and having RNA polymerase activity.
Dependencies are inferred from the claim text.