Use of compounds with a nitrogen-oxygen heterocycle

A method for the treatment of infectious diseases caused by bacteria, fungi or parasites comprising:

• administering to a patient having an infection caused by said bacteria, fungi or parasites a therapeutically effective amount of a compound of formula (I)
• wherein Y is a C1-3-alkylene group, which is substituted by the substituents R1 and R2 and optionally by the substituents R3 to R6,
• wherein R1 to R8 are the same or different and are selected from the group consisting of hydrogen, hydroxy, halogen, substituted and unsubstituted alkyl groups, substituted and unsubstituted cycloalkyl-(C0-26)-alkyl groups, substituted and unsubstituted cycloalkoxy-(C0-26-alkyl groups, substituted and unsubstituted alkoxy (C0-26)-alkyl groups, substituted and unsubstituted amino groups and substituted, unsubstituted thio(C0-26)-alkyl groups, substituted and unsubstituted sulfonyl(C0-26)-alkyl groups, substituted and unsubstituted sulfinyl(C0-26)-alkyl groups and substituted or unsubstituted acyl radicals, wherein each alkyl radical, each alkoxy radical and each acyl radical branched or unbranched and each alkyl radical, each alkoxy radical and each cycloalkyl group is saturated or unsaturated having one or more double or triple bonds and one or two carbon atoms of the cycloalkyl groups may be replaced by nitrogen, oxygen or sulphur atoms, and
• R13 and R14 are defined like R1 to R9 or together form an oxo group,
• wherein X represents the organo phosphorous group,
• wherein R9 and R10 are the same or different and are selected from the group consisting of hydrogen, substituted and unsubstituted (C1-26)-alkyl groups, substituted and unsubstituted hydroxy-(C1-26)-alkyl groups, substituted and unsubstituted cycloalkyl-(C0-26)-alkyl groups, substituted and unsubstituted acyl, halogen, OX9 and OX10, wherein each alkyl radical, each alkoxy radical and each acyl radical branched or unbranched and each alkyl radical, each alkoxy radical and each cycloalkyl group is saturated or unsaturated having one or moore double or triple bonds and one or two carbon atoms of the cycloalkyl groups may be replaced by nitrogen, oxygen or sulphur atoms,
• wherein X9 or X10 may be identical or different and are selected from the group consisting of hydrogen, substituted and unsubstituted (C1-26)-alkyl groups, substituted and unsubstituted hydroxy-(C1-26)-alkyl groups, substituted and unsubstituted cycloalkyl-(C0-26)-alkyl groups, substituted and unsubstituted acyl silyl, a cation of an organic and inorganic base, a metal of main group I, II or m of the periodic system, ammonium, substituted ammonium and ammonium compounds which are derived from ethylenediamine or amino acids, wherein each alkyl radical, each alkoxy radical and each acyl radical branched or unbranched and each alkyl radical, each alkoxy radical and each cycloalkyl group saturated or unsaturated having one or more double bonds or triple bonds and one or two carbon atoms of the cycloalkyl groups may be replaced by nitrogen, oxygen or sulphur atoms, or
• wherein X represents the amino group
• wherein R11 and R12 are the same or different and are selected from the group consisting of hydrogen, substituted and unsubstituted alkyl groups, substituted and unsubstituted cycloalkyl-(C0-26)-alkyl groups, substituted and unsubstituted cycloalkoxy-(C0-26)-alkyl groups, substituted and unsubstituted alkoxy (C0-26)-alkyl groups, and wherein each alkyl radical, each alkoxy radical and each alkyl radical, each alkoxy radical and each cycloalkyl group is saturated or unsaturated with one or more double bonds or triple bonds and one or two carbon atoms of the cycloalkyl groups may be replaced by nitrogen, oxygen or sulphur atoms,
• wherein B is selected from the group consisting of substituted and unsubstituted C1-26-alkylene groups, wherein one C-atom may be replaced by an oxygen atom and one C-atom may be replaced by a sulphur atom or two C-atomns may be replaced by a S-heterocycle and wherein each alkylene radical may be branched or unbranched and is saturated or unsaturated having one or more double bonds or triple bonds and may be substituted with one or more hydroxy groups, halogen groups or oxo groups, or pharnaceutically acceptable salts, esters and salts of the esters for the inhibition of the 1-deoxy-D-xylulose-5-phosphate(DOXP)-metabolic pathway.