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US 6,638,946 B2Granted
Substituted pyridine or piperidine compounds
AssigneeLes Laboratoires Servier
InventorsOtto Meth-Cohn, Chu-Yi Yu, Pierre Lestage, Marie-Cécile Lebrun, Daniel-Henri Caignard, Pierre Renard
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Abstract
The invention relates to a compound of formula (I): wherein: A represents pyridine, pyridinium or piperidine R1, R2, R3 and R4 are as defined in the description R5 represents hydrogen, a nitrogen-containing heterocycle or a group of formula (II): R6 represents hydrogen or linear or branched (C1-C6)alkyl. and medicinal products containing the same which are useful in treating pain or deficiencies in memory.
Claims10
A compound selected from those of formula (I):
- wherein:
- A represents pyridine, pyridinium, or piperidine,
- R2 represents hydrogen and R3 represents hydroxy, or R2 and R3 together form oxo,
- R1 and R4 together with the two carbon atoms carrying them, form a ring containing 6 carbon atoms,
- R5 represents a group of formula (II):
- wherein R′1, R′2, R′3 and R′4 have the same meaning as R1, R2, R3 and R4 respectively,
- R6 represents hydrogen or linear or branched (C1-C6)alkyl, the group R6 being present or absent depending on the nature of the ring A,
- its enantiomers and diastereoisomers, and addition salts thereof with a pharmaceutically-acceptable acid or base.
5 more elements
Dependencies are inferred from the claim text.