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US 6,638,907 B1Granted
Laminin 8 and methods for its use
AssigneeBioStratum, Inc.
InventorsJarrko Kortesmaa, Karl Tryggvason
Life of this patent
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Abstract
The present invention provides substantially purified laminin 8, methods for making recombinant laminin 8, cells that express recombinant laminin 8, and methods for using the recombinant laminin 8 to accelerate the healing of injuries to vascular tissue and tissue of mesenchymal origin, and to promote cell attachment and migration.
Claims3
A pharmaceutical composition comprising:
- a) a substantially purified laminin 8, comprising:
- a first polypeptide chain comprising an amino acid sequence selected from the group consisting of SEQ ID NO:
- 2, SEQ ID NO:
- 4, SEQ ID NO:
- 6, or SEQ ID NO:
- 8, or a secreted form thereof;
- a second polypeptide chain comprising an amino acid sequence selected from the group consisting of SEQ ID NO:
- 14, and SEQ ID NO:
- 16, or a secreted form thereof;
- and
- a third polypeptide chain comprising an amino acid sequence selected from the group consisting of SEQ ID NO:
- 22 or SEQ ID NO:
- 24, or a secreted form thereof;
- and
- b) a pharmaceutically acceptable carrier.
12 more elements
Dependencies are inferred from the claim text.