Composition and method for diagnosing auto-immune hepatitis
OwnerAnsgar W. Lohseinventor
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Abstract
A composition and method for the diagnosis of autoimmune hepatitis. The composition, which contains SLA antigens detects soluble liver antigen (SLA) auto-antibodies, which occur in sera of patients suffering from chronic hepatitis.
Claims10
A method of detecting the presence of soluble liver antigen (SLA) antibodies in a patient's blood serum comprising binding an antigen, wherein said antigen is encoded by DNA sequence SEQ ID NO:1 or has the amino acid sequence SEQ ID NO:2, that is recognized by SLA antibodies to a matrix, detecting binding of said SLA antibodies to said antigen, and correlating said binding to the presence of SLA antibodies in the patient's blood serum.
A method of detecting the presence of soluble liver antigen (SLA) antibodies in a patient's blood serum comprising binding an antigen, wherein said antigen is encoded by DNA sequence SEQ ID NO:3 or has the amino acid sequence SEQ ID NO:4, that is recognized by SLA antibodies to a matrix, detecting binding of said SLA antibodies to said antigen, and correlating said binding to the presence of SLA antibodies in the patient's blood serum.
Dependencies are inferred from the claim text.