Process for preparation of optically active 1,2-diols by cultivating microorganisms
AssigneeDaiso Co., Ltd.
InventorsToshio Suzuki, Hideaki Idogaki, Atsushi Nakagawa
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Abstract
A process for preparation of an optically active 1,2-diol compound of the following formula: wherein R is alkyl group, hydroxy substituted alkyl group, or alkenyl group, which comprises reacting a corresponding racemic 1,2-diol compound with a strain belonging to the genus Alcaligenes which is being cultivated under aeration.
Claims3
A process for preparation of (R)-1,2,4-butanetriol and (S)-2,4-dihydroxybutyric acid which comprises reacting racemic 1,2,4-butanetriol with a strain belonging to the genus Alcaligenes selected from the group consisting of Alcaligenes sp. DS-S-7G (FERMBP-3098), Alcaligenes sp. DS-S-8S (FERM BP-3099) and Alcaligenes sp. DS-S-1C (FERM BP-3100) which is being cultivated under aeration, and recovering said (R)-1,2,4-butanetriol and said (S)-2,4-dihydroxybutyric acid from the resultant culture broth.
A process for preparation of (S)-2,4-dihydroxybutyric acid which comprises reacting racemic 1,2,4-butanetriol with a strain belonging to the genus Alcaligenes selected from the group consisting of Alcaligenes sp. DS-S-7G (FERM BP-3098), Alcaligenes sp. DS-S-8S (FERM BP-3099) and Alcaligenes sp. DS-S-1C (FERM BP-3100) which is being cultivated under aeration, and recovering said (S)-2,4-dihydroxybutyric acid from the resultant culture broth.
A process for preparation of (R)-1,2,4-butanetriol which comprises reacting racemic 1,2,4-butanetriol with a strain belonging to the genus Alcaligenes selected from the group consisting ofAlcaligenes sp. DS-S-7G (FERM BP-3098), Alcaligenes sp. DS-S-8S (FERM BP-3099) and Alcaligenes sp. DS-S-1C (FERM BP-3100) which is being cultivated under aeration, and recovering said (R)-1,2,4-butanetriol from the resultant culture broth.
Dependencies are inferred from the claim text.