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US 6,638,723 B1Granted
Method for diagnosing autoimmune diseases
OwnerThink You Kiminventor
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Abstract
A method of diagnosing an autoimmune disease is disclosed which involves determining whether autoantibodies from a body fluid react with a microtubule organizing center (MTOC). This diagnostic procedure provides a simple, highly specific, and highly reliable diagnosis of autoimmune disease, including rheumatoid arthritis.
Claims5
A method for diagnosing an autoimmune disease, comprising:
- (a) contacting a body fluid of a subject suspected of having an autoimmune disease with a cell having a cytoplasmic microtubule organizing center (MTOC);
- and
- (b) determining whether said MTOC has reacted with autoantibodies (anti-MTOC antibodies) in the body fluid, wherein said reaction is diagnostic of autoimmune disease in the subject, and
- wherein said cell is a macrophage selected from an IT-1 cell line deposited as KFCC 10772.
1 more element
Dependencies are inferred from the claim text.