Reconfigurable detection and analysis apparatus and method

A stacked, reconfigurable detection and analysis apparatus comprising:

• an inlet for receipt of a sample containing charged biological materials;
• a first chamber defined by a bottom support, an intermediate member, and a first spacer, said first chamber being coupled to said inlet through the bottom support, said first chamber including an analysis system, said analysis system including electrodes for the electrical transport and screening of the charged biological materials;
• and
• a second chamber stacked on top of said first chamber, said second chamber defined by the intermediate member, a top member, and a second spacer, said second chamber being in fluid communication with said first chamber through at least one via formed in the intermediate member, the second chamber including one or more electrically reconfigurable arrays disposed therein, the one or more electrically reconfigurable arrays being electrically reconfigurable to perform directed peptide synthesis based the screening of the charged biological materials.

A stacked, reconfigurable detection and analysis apparatus comprising:

• an inlet for receipt of a sample containing charged biological materials;
• a first chamber defined by a bottom support, an intermediate member, and a first spacer, said first chamber being coupled to said inlet through the bottom support, said first chamber including an analysis system, said analysis system including electrodes for the electrical transport and screening of the charged biological materials;
• and
• a second chamber stacked on top of said first chamber, said second chamber defined by the intermediate member, a top member, and a second spacer, said second chamber being in fluid communication with said first chamber through at least one via formed in the intermediate member, the second chamber including one or more electrically reconfigurable arrays disposed therein, the one or more electrically reconfigurable arrays being electrically reconfigurable to synthesize a compound based the screening of the charged biological materials, the second chamber including a detachable support disposed therein, wherein the synthesized compound is anchored to the detachable support, the detachable support being removable from the system and used for injection.

A method for performing analysis on charged biological materials comprising the steps of:

• delivering an airborne sample containing charged biological materials to a first chamber;
• transporting and screening the charged biological materials within the first chamber;
• transporting one or more species contained within the charged biological materials to a second chamber;
• and
• performing one or more specialized assays on the one or more species contained within the second chamber using at least one reconfigurable array, the reconfigurable array being configured based on information obtained from the screening of charged biological materials in said first chamber.

A method for performing analysis on charged biological materials comprising the steps of:

• delivering a sample containing charged biological materials to a first chamber defined by a bottom support, an intermediate member, and a first spacer;
• screening the charged biological materials within the first chamber;
• transporting one or more species contained within the charged biological materials to a second chamber stacked on top of said first chamber, said second chamber defined by the intermediate member, a top member, and a second spacer, said one or more species entering said second chamber through at least one via formed in the intermediate member;
• performing one or more specialized assays on the one or more species contained within the second chamber using at least one electrically reconfigurable array, the electrically reconfigurable array being configured based on information obtained from the screening of charged biological materials in said first chamber;
• and
• synthesizing a compound in said second chamber, wherein the compound is anchored to a detachable support provided in the second chamber.

A method for performing analysis on charged biological materials comprising the steps of:

• delivering a sample containing charged biological materials to a first chamber defined by a bottom support, an intermediate member, and a first spacer;
• screening the charged biological materials within the first chamber;
• transporting one or more species contained within the charged biological materials to a second chamber stacked on top of said first chamber, said second chamber defined by the intermediate member, a top member, and a second spacer, said one or more species entering said second chamber through at least one via formed in the intermediate member;
• performing one or more specialized assays on the one or more species contained within the second chamber using at least one electrically reconfigurable array, the electrically reconfigurable array being configured based on information obtained from the screening of charged biological materials in said first chamber;
• and
• synthesizing a peptide in said second chamber.

A stacked, reconfigurable system for performing analysis on a pathogen, the system comprising:

• an inlet for receipt of a sample including said pathogen,
• a first chamber defined by a bottom support, an intermediate member, and a first spacer, said first chamber being coupled to said inlet through the bottom support, said first chamber including an analysis system, said analysis system including electrodes for the electrophoretic transport of said pathogen, and an analysis system for determining at least certain information regarding said pathogen,
• a second chamber stacked on top of said first chamber, said second chamber defined by the intermediate member, a top member, and a second spacer, said second chamber being in fluid communication with said first chamber through at least one via formed in the intermediate member, said second chamber being electrically reconfigurable to permit action with respect to a plurality of pathogens, wherein the reconfigurable system is configured based at least in part upon the analysis in said first chamber, and
• an air handling system comprising an electrostatic generator coupled to the inlet.

A stacked, reconfigurable detection and analysis apparatus comprising:

• an inlet for receipt of a sample containing charged biological materials;
• a first chamber defined by a bottom support, an intermediate member, and a first spacer, said first chamber being coupled to said inlet through the bottom support, said first chamber including an analysis system, said analysis system including electrodes for the electrical transport and screening of the charged biological materials;
• a second chamber stacked on top of said first chamber, said second chamber defined by the intermediate member, a top member, and a second spacer, said second chamber being in fluid communication with said first chamber through at least one via formed in the intermediate member, the second chamber including one or more electrically reconfigurable arrays disposed therein, the one or more electrically reconfigurable arrays being electrically reconfigurable to perform specialized analysis based the screening of the charged biological materials;
• and
• an air handling system comprising an electrostatic generator coupled to the inlet.