Radioactive medical device for radiation therapy
AssigneeMDS (Canada) Inc.
InventorsAlbert Chan, Corinne Bensimon
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Abstract
The present invention discloses a radioactive medical device comprising a radioactive, electroplated substrate coated with at least one layer of polymer and sealed in a jacket layer. The at least one layer of polymer and jacket layer reduce leaching of a radioactive element from the electroplated substrate. The radioactive medical device is useful for radiation therapy of diseased tissue such as cancers and especially malignant tumors.
Claims20
A radioactive medical device comprising a radioactive, electroplated substrate coated with at least one layer of polymer and sealed with a nonmetallic jacket layer, wherein the amount of radioactivity per unit area of said radioactive, electroplated substrate is from about 100 mCi/mm2 to about 200 mCi/mm2.
A radioactive medical device comprising a silver wire substrate electroplated with radioactive iodine to form a radioactive, electroplated wire substrate, said radioactive, electroplated wire substrate coated with at lease one layer of polyurethane and sealed with a non-metallic jacket layer, wherein the amount of radioactivity per unit area of said radioactive, electroplated substrate is from about 100 mCi/mm2 to about 200 mCi/mm2.
A method of manufacturing a radioactive medical device comprising the steps of:
- a) electroplating a substrate with a radioactive element to form a radioactive, electroplated substrate, wherein the amount of radioactivity per unit area of said radioactive, electroplated substrate is from about 100 mCi/mm2 to about 200 mCi/mm2;
- b) coating the radioactive, electroplated substrate with at least one layer of polymer to form a radioactive, electroplated substrate coated with at least one layer of polymer;
- and
- c) sealing the radioactive, electroplated substrate coated with at least one layer of polymer in a jacket layer.
A method of manufacturing a radioactive medical device comprising the steps of:
- a) electroplating a substrate with a radioactive element to form a radioactive, electroplated substrate at a current of from about 10-100 μA;
- b) coating the radioactive, electroplated substrate with at least one layer of polymer to form a radioactive, electroplated substrate coated with at least one layer of polymer and;
- c) sealing the radioactive, electroplated substrate coated with at least one layer of polymer in a jacket layer.
Dependencies are inferred from the claim text.