US 6,635,757 B1 · Process for preparing cyclodextrin inclusion complex

Abstract

The present invention relates to a process for the preparation of a water soluble inclusion complex of neem seed kernel extract (NSKE) containing azadirachtin-A in cyclodextrin and its use in an insecticidal formulation. The process of the present invention comprises the following steps adding neem seed kernel extract containing azadirachtin-A to cyclodextrin, the molar ratio of azadirachtin-A to the cyclodextrin ranging from 1:0.5 to 1:20, stirring the above mixture, filtering the above mixture to obtain a water soluble inclusion complex of neem seed kernel extract, if desired, freeze/spray drying the said water soluble complex of neem seed kernel extract to get a free flowing pale cream powder.

Claims10

Dependent claims

Insecticidal formulation including inclusion complex of neem seed kernel extract (NSKE) containing azadirachtin-A comprising:

a solution of inclusion complex containing cyclodextrin and neem seed kernel extract containing predominantly azadirachtin-A in water in the range of 0.1 to 1000 ppm with respect to azadirachtin-A, and
if desired, 0.001%-25% of sun screen agents or salicylic acid either alone or in combination based on azadirachtin-A content in the inclusion complex ranging from 1% to 50% (wt/wt) for enhancing the shelf life and in plant defense mechanism against pathogen to have multiple effect.

Dependencies are inferred from the claim text.

Process for preparing cyclodextrin inclusion complex

Life of this patent

Process for preparing cyclodextrin inclusion complex

Life of this patent

Abstract

Claims10