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US 6,635,752 B2Granted
Variant of LAV viruses
AssigneeInstitut Pasteur
InventorsMarc Alizon, Pierre Sonigo, Simon Wain-Hobson, Luc Montagnier
Life of this patent
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Abstract
A variant of a LAV virus, designated LAVMAL and capable of causing AIDS. The cDNA and antigens of the LAVMAL virus can be used for the diagnosis of AIDS and pre-AIDS.
Claims2
A recombinant plasmid comprising a cDNA fragment comprising at least a first nucleotide sequence selected from the group consisting of:
- A. a sequence comprising nucleotides 1 to 96;
- B. a sequence comprising nucleotides 97 to 179;
- C. a sequence comprising nucleotides 8676 to 9133;
- D. a sequence comprising nucleotides 9134 to 9229;
- E. a sequence comprising nucleotides 5405 to 5620;
- F. a sequence comprising nucleotides 5134 to 5421;
- G. a sequence comprising nucleotides 8380 to 9006;
- H. a sequence comprising nucleotides 350 to 1864;
- I. a sequence comprising nucleotides 1663 to 4668;
- J. a sequence comprising nucleotides 5799 to 8375;
- K. a sequence comprising nucleotides 764 to 1501;
- L. a sequence comprising nucleotides 1502 to 1864;
- M. a sequence comprising nucleotides 5799 to 5885;
- N. a sequence comprising nucleotides 5886 to 7337;
- O. a sequence comprising nucleotides 7377 to 8375;
- P. a sequence comprising nucleotides 5895 to 6176;
- Q. a sequence comprising nucleotides 6399 to 6635;
- R. a sequence comprising nucleotides 7212 to 7337;
- S. a sequence comprising nucleotides 7215 to 7604;
- T. a sequence comprising nucleotides 7782 to 7844;
- of FIGS. 7A-7I,
- wherein the plasmid is capable of being transfected in a host cell, and is capable of being expressed in a host cell.
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Dependencies are inferred from the claim text.