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US 6,635,749 B2Granted
Isolated nucleic acids comprising Listeria dal and dat genes
AssigneeThe Trustees of the University of Pennsylvania
InventorFred R. Frankel
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Abstract
The invention includes auxotrophic attenuated mutants of Listeria and methods of their use as vaccines.
Claims1
An isolated nucleic acid sequence wherein said isolated nucleic acid sequence is from about 80% to about 100% homologous to the Listeria dat gene set forth in SEQ ID NO:5.
Dependencies are inferred from the claim text.