Remedies or preventives for pulmonary insufficiency containing diaminotrifluoromethylpyridine derivatives
AssigneeIshihara Sangyo Kaisha, Ltd.
InventorsKyuya Morino, Shuichi Yotsuya, Masashi Imamura
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AssigneeIshihara Sangyo Kaisha, Ltd.
InventorsKyuya Morino, Shuichi Yotsuya, Masashi Imamura
Estimating the term…
A therapeutic or preventive agent for pulmonary insufficiency, containing as an active ingredient a diaminotrifluoromethylpyridine derivative represented by the formula (I) or its salt: wherein X is a —CW1R1 group, a —COCOR2 group, a —CW1NHCOR2 group, a —C(═W1)W2R3 group or a —CW1N(R4)R5 group; Y is an alkyl group, a —CW3R6 group, a —COCOR7 group, a —NHCOR7 group, a —C(═W3)W4R8 group, a —(NH)mSO2R9 group, a —(NH)mSO2OR10 group or a —(NH)mSO2N(R11)R12 group; each of R1, R6 and R9 is a chain hydrocarbon group, a monocyclic hydrocarbon group, a polycyclic hydrocarbon group, a monocyclic heterocycle group or a polycyclic heterocycle group; each of R2 and R7 is an alkyl group, an alkoxy group, a phenyl group or a phenoxy group; each of R3, R8 and R10 is an alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, a phenyl group or a benzyl group; each of R4, R5, R11 and R12 is an alkyl group; each of W1, W2, W3 and W4 is an oxygen atom or a sulfur atom; and m is 0 or 1, is provided.
A method for preventing or treating pulmonary insufficiency, comprising administering to a subject in need thereof an effective amount of a diaminotrifluoromethylpyridine compound or its salt, wherein said compound is represented by formula (I):
Dependencies are inferred from the claim text.