Inhibitors of p38

A compound having the formula:

• or tautomers thereof or pharmaceutically acceptable salts thereof;
• wherein:
• HET is a 5-7-membered heterocycle with 1 to 4 ring N, S or O atoms, which heterocycle is substituted with 1 to 3 C1-C4 branched or straight chain alkyl groups;
• wherein HET is optionally substituted with halo, cyano, N(R′)2, OR′CO2R′, CON(R′)2, or SO2N(R2)2;
• X is O or NR′;
• n is 1 to 3;
• each R′ is independently selected from hydrogen, (C1-C3)-alkyl, (C2-C3)-alkenyl or alkynyl, phenyl or phenyl substituted with 1 to 3 substituents independently selected from halo, methoxy, cyano, nitro, amino, hydroxy, methyl or ethyl;
• or a 5-6 membered heterocyclic ring system optionally substituted with 1 to 3 substituents independently selected from halo, methoxy, cyano, nitro, amino, hydroxy, methyl, or ethyl;
• R1 is selected from hydrogen, (C1-C3)-alkyl, OH, or O—(C1-C3)-alkyl;
• R2 is selected from hydrogen, (C1-C3)-alkyl, or (C2-C3)-alkenyl;
• each optionally substituted with —N(R′)2, —OR′, SR′, —C(O)—N(R′)2, —S(O2)—N(R′)2, —C(O)—OR′, or R3;
• and
• R3 is selected from 5-6 membered aromatic carbocyclic or heterocyclic ring systems.