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US 6,635,624 B1Granted
Nucleotide vector composition containing such vector and vaccine for immunization against hepatitis
AssigneesInstitut Pasteur, Institut National de la Sant et de la Recherche Medical, Universite d'Ottawa
InventorsHeather Lynn Davis, Robert Gerald Whalen, Marie-Louise Michel
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Abstract
The invention relates to methods of inducing an immunogenic response in a subject that include administering a nucleotide plasmid vector that includes a gene coding for a surface antigen protein derived from hepatitis B virus and a promoter for the expression of the gene. The invention also relates to vaccine compositions for protecting against hepatitis B virus.
Claims28
A method of inducing an immunogenic response in a subject comprising
- administering a nucleotide plasmid vector, wherein the vector includes a gene coding for a surface antigen protein derived from hepatitis B virus and a promoter for the expression of the gene in the subject.
A vaccine for protecting a mammal against hepatitis B virus, comprising:
- a nucleotide plasmid vector, wherein the vector includes a gene coding for a surface antigen protein derived from hepatitis B virus, and a promoter for the expression of the gene in the mammal, and
- a vaccine adjuvant.
Dependencies are inferred from the claim text.