Hydroxyproline derivatives
AssigneeJapan Bioproducts Ind. Co., Ltd.
InventorsAkira Yagi, Takao Shida, Kokushin Ryu, Taiichi Kaku
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Abstract
The present invention relates to hydroxyproline derivatives represented by the following general formulas and the therapeutic agent containing the same for the impaired organs and tissues. (wherein R is hydrogen or optionally substituted alkyl) The hydroxyproline derivatives of the present invention possess cell-proliferative and cell-protective activities, and are effectively applied for the restoration and regeneration of impaired organs and tissues.
Claims3
A hydroxyproline derivative represented by the general formula (3):
- wherein R is a hydroxymethyl group, wherein the hydroxyproline derivative is essentially pure.
A method of treatment of damaged organs and tissues, which comprises:
- administering to a mammal in need thereof an effective amount of hydroxyproline derivative represented by the general formula (3):
- wherein R is a hydroxymethyl group, wherein the hydroxyproline derivative is administered to a mammal in a concentration of 0.5-100 mg per body weight kg.
Dependencies are inferred from the claim text.