WIP, a WASP-associated protein

An isolated fragment of SEQ ID NO:1 which encodes WIP, a WASP-interacting protein, wherein the fragment includes at least 10 consecutive nucleotides in the coding region of SEQ ID NO:

• 1 which are 5′ of nucleotide 380 of SEQ ID NO:
• 1.

An isolated nucleic acid which encodes WIP, a WASP-interacting protein, and which selectively hybridizes under moderately stringent hybridization conditions to the complement strand of SEQ ID NO:

• 1, said moderately stringent hybridization conditions comprising washing with 0.5×SSC containing 0.1% SDS at 65° C. for 1 hour, and wherein said isolated nucleic acid comprises at least 10 consecutive nucleotides of the coding region of SEQ ID NO:
• 1 which are 5′ of nucleotide 380 of SEQ ID NO:
• 1.

A method for producing a WASP-interacting protein comprising:

• a) introducing into a host cell a nucleic acid construct comprising a nucleic acid comprising full length SEQ ID NO:1;
• and
• b) maintaining the host cell produced in step a) under conditions whereby the nucleic acid is expressed and the WASP-interacting protein is produced.

A isolated nucleic acid which encodes an amino acid sequence comprising SEQ ID NO:2.

An isolated nucleic acid comprising of SEQ ID NO:1.

An isolated nucleic acid which encodes SEQ ID NO:2.

An isolated nucleic acid fragment of SEQ ID NO:

• 1, wherein the fragment includes at least 10 consecutive nucleotides in the coding region of SEQ ID:
• 1 which are 5′ of nucleotide 380 of SEQ ID:
• 1.