Mixed intercalator and electrochemical detection of DNA using same
AssigneeMitocon Ltd.
InventorsYoungmi Kim Pak, James Jungho Pak, Sanghee Kim, Hong-Kyu Lee
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Abstract
Described in the present invention are a highly sensitive method for electrochemically detecting a DNA using a novel mixed intercalator and a detection kit useful for practicing said method.
Claims4
A method for detecting a DNA having a specified base sequence (target DNA), which comprises bringing a single strand of the target DNA (target ssDNA) into contact with a single strand probe DNA (probe ssDNA) bonded on the surface of an electrode equipped with an output terminal to form a double strand DNA (dsDNA), adding a mixed intercalator consisting of compounds of formulae (I) and (II) to intercalate the dsDNA therewith, and determining the current generated when a voltage is applied to the electrode:
A mixed intercalator which consist s of compounds of formulae (I) and (II).
Dependencies are inferred from the claim text.