Pharmaceutical formulations

The composition comprising about 10 mg of 9-[2-[[bis[(pivaloyloxy)-methyl]phosphono]methoxyl]ethyl]adenine, about 1-5 mg magnesium carbonate or calcium carbonate, about 4-8 mg croscarmellose sodium, about 5 mg pregelatinized starch, about 40-65 mg lactose, about 15-35 mg microcrystalline cellulose, about 0-6 mg talc, and about 0.5-2 mg magnesium stearate.

The composition comprising about 30 mg of 9-[2-[[bis[(pivaloyloxy)-methyl]phosphono]methoxyl]ethyl]adenine, about 410 mg magnesium carbonate, 61.5-75.25 mg lactose monohydrate or anhydrous lactose, about 22.5 mg of microcrystalline cellulose, about 7.5 mg of pregelatinized starch, about 9 mg of croscarmellose sodium, about 0-9 mg talc and about 0.75-1.5 mg magnesium stearate.

The composition comprising about 60 mg of 9-[2-[[bis[(pivaloyloxy)-methyl]phosphono]methoxyl]ethyl]adenine, about 12 mg magnesium carbonate, about 73 mg lactose monohydrate or anhydrous lactose, about 30 mg of microcrystalline cellulose, about 10 mg of pregelatinied starch, about 12 mg of croscanellose sodium, about 1 mg silicon dioxide and about 2 mg magnesium stearate.

The composition comprising about 120 mg of 9-[2-[[bis[(pivaloyloxy)-methyl]phosphono]methoxyl]ethyl]adenine, about 12-24 mg magnesium carbonate, about 124-162 mg lactose monohydrate or anhydrous lactose, about 60 mg microcrystalline cellulose, about 20 mg pregelatinized starch, about 24 mg of croscarmellose sodium, about 0-24 mg talc and about 2-4 mg magnesium stearate.

The composition comprising about 4-8% w/w of 9-[2-[[bis[(pivaloyloxy)-methyl]phosphono]methoxyl]ethyl]adenine, about 16-% w/w magnesium carbonate, about 24-51% w/w L-carnitine-L-tartrate, about 20-36% w/w niicrocrystalline cellulose, about 5% w/w pregelatinized starch, about 4% w/w croscarmellose sodium and (1) about 1% w/w sodium stearyl fumarate or (2) about 2% w/w talc and about 1% w/w type I hydrogenated vegetable oil.