Methods of stabilizing silicone hydrogels against hydrolytic degradation
AssigneeJohnson & Johnson Vision Care, Inc.
InventorsDouglas G. Vanderlaan, Stephen L. Galas
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Abstract
A method of increasing the shelf life of silicone hydrogels stored in aqueous solutions. More specifically, the present invention relates to a method of stabilizing a silicone hydrogel article against hydrolytic degradation comprising, storing said silicone hydrogel in an ozone-free, aqueous solution having a pH of from about 5.0 to less than about 7.2, and a viscosity of less than about 10 centipoise, wherein if the aqueous solution is substantially free of poloxamine or poloxamer surfactants.
Claims10
A method comprising stabilizing a silicone hydrogel article against hydrolytic degradation by, storing said silicone hydrogel in an ozone-free, aqueous solution having a pH of from about 5.0 to less than about 7.2, and a viscosity of less than about 10 centipoise, wherein the aqueous solution optionally contains a poloxamine or poloxamer surfactant, in an amount less than about 0.005 weight percent.
An article comprising a silicone hydrogel contact lens stabilized against hydrolytic degradation by the step comprising storing said silicone hydrogel in an ozone-free, aqueous solution having a pH of from about 5.0 to less than about 7.2, and a viscosity of less than about 10 centipoise, wherein the aqueous solution optionally contains a poloxamine or poloxamer surfactant, in an amount less than about 0.005 weight percent.
Dependencies are inferred from the claim text.