Method for separating a diphosphine diastereoisomers
AssigneeRhodia Chimie
InventorsMichel Spagnol, Francois Mathey, Francois Mercier, Frederic Robin
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Abstract
A process for separating the (d/l) and (meso) diastereoisomers of bis-[1-phospha-2,3-diphenyl-4,5-dimethylnorbornadiene] comprising converting the mixture of diastereoisomers of bis-[1-phospha-2,3-diphenyl-4,5-dimethylnorbornadiene] to a mixture of the corresponding diastereoisomers of diphosphine disulphide or dioxide, then in separating the two diastereoisomers in dioxide or disulphide form.
Claims26
A process for separating the racemic (Ir) and meso (Im) diastereoisomers of bis-[1-phospha-2,3-diphenyl-4,5-dimethylnorbornadiene] from a mixture thereof, wherein Ir and Im correspond to the formulae:
- the process comprising converting the mixture of the diastereoisomers of bis-[1-phospha-2,3-diphenyl-4,5-dimethylnorbornadiene] to a mixture of the corresponding diastereoisomers of diphosphine disulphine or dioxide, and then separating the diastereoisomers in dioxide form (IXr and IXm) or disulphide form (IX′r and IX′m), wherein IXr and IXm correspond to the formulae:
- and wherein IX′r and IX′m correspond to the formulae:
Bis-[1-phospha-2,3-diphenyl-4,5-dimethylnorbornadiene]dioxide corresponding to the following formula:
Diphosphine dioxide of bis-[1-phospha-2,3-diphenyl-4,5-dimethylnorbornadiene] corresponding to the following formulae:
- in meso form:
- or in racemic form:
Dependencies are inferred from the claim text.